Liver Cancer Treatment Advantage

Liver Cancer

The CyberKnife® Advantage

The CyberKnife® System's robotic design enables the clinician to approach tumors from many different directions in order to minimize radiation exposure to healthy liver tissue and nearby organs

The CyberKnife System is extraordinarily precise, enabling clinicians to deliver individualized treatment with sub-millimeter accuracy. Radiation is targeted to where it counts – the tumor – and falls off steeply near the healthy tissue and structures surrounding the tumor.

Throughout the treatment, the CyberKnife System tracks the position of the tumor and simultaneously moves the robot to deliver the radiation beam precisely to the moving target. Abdominal tumors, such as liver tumors, move with a patient's respiration. Preserving as much healthy liver tissue as possible makes the ability to track, detect, and correct for this motion critically important.

  • Patient Comfort

    Liver treatments are typically delivered using the Synchrony® Respiratory Tracking System. This highly sophisticated technology locks the robotic motion on to the target in such a way that the robot almost breathes with the patient. The Synchrony System enables patients to breathe naturally throughout the treatment.

    The CyberKnife System's unique robotic design and motion management technology enables clinicians to deliver radiation to a smaller volume – not to a larger volume encompassing the tumor's range of motion.

  • Clinically Proven

    A study of 75 patients with liver cancer treated using the CyberKnife® System found that 89.8 percent of patients showed no progression of cancer beyond the liver two years following treatment. Overall survival at the one year follow-up was 78.5 percent and at the two year follow-up was 50.4 percent.1

    A study evaluating the efficacy and toxicity of SBRT in the treatment of 57 patients with liver metastases showed more than 85 percent of patients achieved local tumor control at two years' post treatment, without severe toxicities. Overall survival at the two-year follow-up was 55.9 percent. SBRT with the CyberKnife System is an effective alternative for those patients with liver metastases who cannot undergo surgery and/or whose tumors cannot be completely removed with surgery.2

  • Alternate to Surgery

    Treatments with the CyberKnife System are non-invasive and pain free.

    In some cases, CyberKnife radiosurgery may be an alternative to traditional surgery. It does not typically require anesthesia or an overnight hospital stay, and eliminates the recovery time and risks associated with surgery.

  • Convenient Treatment Schedule

    Most cases are treated in one to five treatment sessions, typically performed on an outpatient basis over the course of consecutive days and requiring no overnight hospital stays.

  • Retreatment

    Because it can precisely target tumors, the CyberKnife System may provide a safe radiation treatment option even for some previously irradiated patients.

  • Talk to Your Doctor

    Although most patients experience minimal side effects of liver SBRT, side effects can occur and may be severe. Discuss these with your doctor to determine whether you are a candidate for liver SBRT with the CyberKnife.

    What makes CyberKnife radiosurgery different »

    Radiation therapy is completely non-invasive. In some cases, tiny gold markers (fiducials) that help distinguish the tumor from non-cancerous soft tissue are implanted with a minimally invasive procedure.

1. Bibault, J-E, S. Dewas, S, Vautravers-Dewas C, Hollebecque A, Jarraya H, et al. Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Prognostic Factors of Local Control, Overall Survival, and Toxicity. PLoS One. 2013; 8(10): e77472. Published online 2013 Oct 11. doi: 10.1371/journal.pone.0077472
2. Yuan ZY, Meng MB, Liu CL, Wang HH, et al. Stereotactic Body Radiation Therapy Using the CyberKnife® System for Patients with Liver Metastases. Onco Targets Ther. 2014 Jun 12;7:915-23.